ALEXANDRIA, Va., June 16 -- United States Patent no. 12,303,558, issued on May 20, was assigned to University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh).

"Cancer prevention and therapy by inhibiting soluble tumor necrosis factor" was invented by Nikola L. Vujanovic (Pittsburgh) and Lazar Vujanovic (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods are disclosed for inhibiting the development of a tumor in a subject. The methods include administering to a subject a therapeutically effective amount of a dominant negative tumor necrosis factor (DN-TNF)-Alpha protein and/or a nucleic acid encoding the DN-TNF-Alpha protein. The DN-TNF-Alpha protein and/or a nucleic a...