US Patent Issued to University of Pittsburgh-Of The Commonwealth System of Higher Education on March 25 for "Biomarkers related to organ function" (Pennsylvania Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,259,397, issued on March 25, was assigned to University of Pittsburgh-Of The Commonwealth System of Higher Education (Pittsburgh).

"Biomarkers related to organ function" was invented by Paulo Artur Chaves Fontes (Pittsburgh) and John A. Kellum (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of identifying biomarkers (such as genes (e.g., RNA or mRNA), proteins, and/or small molecules) that can be used to predict organ or tissue function or dysfunction. In some embodiments, the methods include ex vivo perfusion of the organ or tissue, collection of samples from the organ or tissue (for example, perfusate, fluids p...