ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,159, issued on Dec. 9, was assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh).

"Controlled release formulations for the induction and proliferation of blood cells" was invented by Steven R. Little (Pittsburgh), Giorgio Raimondi (Pittsburgh), Angus W. Thomson (Pittsburgh) and Siddharth Jhunjhunwala (Chennai, India).

According to the abstract* released by the U.S. Patent & Trademark Office: "The absence of regulatory T cells (Treg) may underlie disorders including but not limited to autoimmunity, dermatitis, periodontitis and even transplant rejection. Enhancing local numbers of Treg through in situ Treg expansion or induction is contemp...