ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,653, issued on Dec. 30, was assigned to University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh).
"Organ chip to model mammalian joint" was invented by Hang Lin (Pittsburgh), Rocky Sung Chi Tuan (Pittsburgh) and Michael Seth Gold (Oakmont, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are various bioreactor devices that mimic the mammalian joint. The bioreactor device can include a series of bioreactor chambers that contain different components of the joint, such as bone, cartilage, synovium, nerve and ligament. At least two different nutrient fluid circulation systems connect subsets of the bioreact...