ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,176, issued on May 13, was assigned to University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh) and Universite Le Havre Normandie (Le Havre, France).

"Compounds and methods for inhibiting EMT pathways to treat cancer, organ fibrosis and metabolic disorders" was invented by Abdelhadi Rebbaa (Northvale, N.J.), Sebastien Comesse (Yvetot, France), Adam Daich (Cauville sur Mer, France), Martin Lawson (Les Loges, France) and Catalin Pintiala (Lille, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "A compound, or a pharmaceutically acceptable salt or isomer thereof, of Formula I: wherein R is hydrogen, alkyl, substituted al...