US Patent Issued to University of Miami, StemSynergy Therapeutics on April 15 for "Inhibitors of the notch transcriptional activation complex and methods for use of the same" (Florida, New Hampshire Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,725, issued on April 15, was assigned to University of Miami (Miami) and StemSynergy Therapeutics Inc. (Miami).

"Inhibitors of the notch transcriptional activation complex and methods for use of the same" was invented by Anthony J. Capobianco (Miami Beach, Fla.), Mark Spyvee (Hampstead, N.H.), Luisana Astudillo (North Miami, Fla.) and Darren Orton (Miami).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are inhibitors of the Notch transcriptional activation complex, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically accep...