US Patent Issued to University of Massachusetts on Oct. 21 for "rAAV vectors for the treatment of GM1 and GM2 gangliosidosis" (Massachusetts Inventor)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,629, issued on Oct. 21, was assigned to University of Massachusetts (Boston).

"rAAV vectors for the treatment of GM1 and GM2 gangliosidosis" was invented by Miguel Sena Esteves (Westford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to compositions and methods for the treatment of lysosomal storage disorders, such as GM1 gangliosidosis, Tay Sachs disease, and Sandhoff disease. In some embodiments, the compositions comprise viral vectors encoding beta-galactosidase. In some embodiments, the compositions comprise viral vectors encoding beta-hexosaminidase subunits (e.g. HEXA, HEXB, or combinations thereof)."

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