ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,358, issued on Oct. 21, was assigned to University of Massachusetts (Westborough, Mass.).

"Inhibitors of protein arginine deiminase 1 and methods of preparation and use thereof" was invented by Paul R. Thompson (Wellesley, Mass.) and Santanu Mondal (Shrewsbury, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides novel inhibitors or inactivators of protein arginine deiminase 1, pharmaceutical compositions and methods of use thereof. The invention also relates to molecular probes based on such compounds and methods of use thereof."

The patent was filed on June 26, 2020, under Application No. 17/622,200.

*For further informati...