US Patent Issued to University of Maryland on Aug. 12 for "Doxorubicin containing nanoplexes and uses thereof" (Maryland Inventor)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,632, issued on Aug. 12, was assigned to University of Maryland (Baltimore).

"Doxorubicin containing nanoplexes and uses thereof" was invented by Archibald James Mixson (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides tumor-targeting nanoplexes. Generally, a tumor-targeting nanoplex is a chemotherapeutic agent DNA conjugate with a first tumor-targeting agent and an optional second tumor-targeting agent linked thereto, such as a doxorubicin plasmid DNA conjugate and a linear histidine-lysine peptide with an optional cRGD-PEG-H3K4b second targeting agent. Also provided are methods for treating a cancer in a ...