US Patent Issued to University of Maryland, College Park on June 3 for "ICAM-1 targeted fusion enzymes" (American, Chinese Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,719, issued on June 3, was assigned to University of Maryland, College Park (College Park, Md.).

"ICAM-1 targeted fusion enzymes" was invented by Silvia Muro (Gaithersburg, Md.), Jing Chen (Nanjing, China), Melani Solomon (Laurel, Md.) and Kevin Gray (Washington).

According to the abstract* released by the U.S. Patent & Trademark Office: "Proteins, nucleic acids encoding the proteins, compositions comprising the proteins, and methods are provided. The proteins have the ability to be self-targeted to ICAM-1 and, if desired, enzymatically-released at acidic pH. The ICAM-1-targeting peptides are provided as single copies or multiples repeats, and can be separated by linkers from the ...