US Patent Issued to UNIVERSITY OF HOUSTON SYSTEM on July 15 for "Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures" (Texas Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,610, issued on July 15, was assigned to UNIVERSITY OF HOUSTON SYSTEM (Houston).

"Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures" was invented by Anton Dubrovskiy (Houston) and Arcadius V. Krivoshein (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aryl-substituted acetamide and pyrrolidin-2-one (Gamma-butyrolactam) derivatives have useful activity in the inhibition, prevention, or treatment of seizures. The derivatives may be useful in the treatment of epilepsy, including medically refractory epilepsy, and nerve agent poisoning."

The patent was filed on Sept. 7, 2023, under Application...