US Patent Issued to University of Cincinnati on July 15 for "Compositions and methods for treating defects in avascular cartilaginous tissue by directly administering one or more metabolites of simvastatin" (Ohio Inventor)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,606, issued on July 15, was assigned to University of Cincinnati (Cincinnati).

"Compositions and methods for treating defects in avascular cartilaginous tissue by directly administering one or more metabolites of simvastatin" was invented by Chia-Ying James Lin (Mason, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Controlled release hydrogel formulations of one or more simvastatin metabolites 3'-hydroxy simvastatin (hSV), 6'-exomethylene simvastatin (eSV), 3',5'-dihydrodiol simvastatin, 3',5'-dihydrodiol simvastatin (dSV), simvastatin-beta-hydroxy acid (SVA), and methods for the treatment of patients suffering from injured or degenerating subs...