ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,537, issued on Aug. 12, was assigned to UNIVERSIDADE DE COIMBRA (Coimbra, Portugal) and UNIVERSIDADE DO PORTO (Oporto, Portugal).

"(3S)-and (3R)-6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-cthiazoles as P53 activators" was invented by Lucilia Helena Ataide Saraiva (Oporto, Portugal), Joana Oliveira Gama Soares (Oporto, Portugal), Teresa Margarida Vasconcelos Dias De Pinho E Melo (Coimbra, Portugal), Maria Isabel Lopes Soares (Coimbra, Portugal) and Helena Isabel Nogueira Ramos Rocha (Oporto, Portugal).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application relates to compounds of formula I, which are (3S)- and (3R)-6,7-bis(Hydroxymethyl)-...