ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,472,249, issued on Nov. 18, was assigned to UCL Business LTD (London) and London School of Hygiene & Tropical Medicine (London).

"Glyconjugate vaccines" was invented by Brendan Wren (London), Jeremy Brown (London) and Jon Cuccui (London).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to the use of S. pneumoniae protein antigens, such as NanA, PiuA and Sp0148, as carriers for immunogenic S. pneumoniae capsular polysaccharide. This may be useful for example in glycoconjugate vaccines able to generate a protective immune response against multiple capsular serotypes. Glycoconjugates, vaccine compositions and methods of manufacture and ...