ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,441, issued on Dec. 30, was assigned to TYK MEDICINES (ZHENGZHOU) INC. (Henan, China) and TYK MEDICINES INC. (Zhejiang, China).

"Compounds used as kinase inhibitors and application thereof" was invented by Jun Li (Henan, China), Chengshan Niu (Henan, China), Apeng Liang (Henan, China), Zhongwei Guo (Henan, China) and Yusheng Wu (Henan, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A kinase inhibitor compound of formula I or a pharmaceutically acceptable salt, solvate, or prodrug thereof. The compound has good inhibitory activity on EGFR and Her2 exon 20 insertion mutation, EGFR exon 19 deletion and L858R point mutation of exon 21."

The paten...