US Patent Issued to TSRL, Regents of the University of Michigan on Aug. 26 for "Metabolically stable prodrugs" (Michigan Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,397,058, issued on Aug. 26, was assigned to TSRL Inc. (Ann Arbor, Mich.) and Regents of the University of Michigan (Ann Arbor, Mich.).

"Metabolically stable prodrugs" was invented by Elke Lipka (Ann Arbor, Mich.), Eric Simon (Chelsea, Mich.), Andy D. White (Pinckney, Mich.), Kim M. Hutchings (Dexter, Mich.) and Xinmin Gan (Ann Arbor, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are prodrugs of various therapeutic agents that provide enhanced bioavailability of the therapeutic agent, and methods of treatment conditions in a subject by administration of the one or prodrugs. As provided herein a prodrug includes a therapeutic agent covalen...