US Patent Issued to Trustees of Tufts College on Feb. 3 for "Anti-ADAM8 antibodies and uses of the same" (Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,193, issued on Feb. 3, was assigned to Trustees of Tufts College (Medford, Mass.).

"Anti-ADAM8 antibodies and uses of the same" was invented by Gail Sonenshein (Brookline, Mass.) and Nora Mineva (Brighton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are proteins that inhibit both the metalloprotease activity and disintegrin activity of human ADAM8, wherein the protein comprises an antigen-binding domain that: (i) binds specifically to human ADAM8; and (ii) binds to an epitope within human ADAM8 that includes at least one amino acid within the sequence of SEQ ID NO: 1, nucleic acids, vectors, compositions, and methods of use t...