ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,847, issued on Sept. 23, was assigned to Trustees of Dartmouth College (Hanover, N.H.).

"Composition and method for attenuating neuroinflammation, amyloidopathy and tauopathy" was invented by Ta Yuan Chang (Etna, N.H.), Catherine C.Y. Chang (Etna, N.H.), Haibo Li (Hanover, N.H.), Adrianna De La Torre (Lyme, N.H.) and Thao N. Huynh (Concord, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features compositions and methods for preventing or treating neuroinflammation, amyloidopathy or tauopathy by inhibiting Acyl-CoA:Cholesterol Acyltransferase activity, in particular with brain-permeable inhibitors encapsulated in a stealth...