US Patent Issued to Trustees of Dartmouth College on Dec. 16 for "System and method for quantitative dosimetry of photodynamic therapy in skin" (New Hampshire, Vermont Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,460, issued on Dec. 16, was assigned to Trustees of Dartmouth College (Hanover, N.H.).

"System and method for quantitative dosimetry of photodynamic therapy in skin" was invented by Alberto J. Ruiz (Hanover, N.H.), Ethan P. M. Larochelle (Thetford Center, Vt.) and Brian Pogue (Hanover, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "While clinical treatment of actinic keratosis by photodynamic therapy (PDT) is widely practiced, there is well-known variability in response, primarily caused by heterogeneous accumulation and PDT-induced photobleaching of the photosensitizer protoporphyrin IX (PpIX) between patients and between lesions. One of the k...