ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,157, issued on Sept. 9, was assigned to TOYAMA PREFECTURAL UNIVERSITY (Toyama, Japan), TEIKA PHARMACEUTICAL Co. LTD. (Toyama, Japan) and NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Tokyo).
"Compound useful as toll-like receptor 7 activation inhibitor" was invented by Yoshinori Nagai (Toyama, Japan), Naoki Okamoto (Toyama, Japan), Shigeto Fujishita (Toyama, Japan) and Takatsugu Hirokawa (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "CB-7 exhibits a weak TLR7 inhibiting effect in normal mice. The present invention provides a novel compound with a stronger TLR7 inhibiting effect than CB-7, a pharmaceutically acceptable sal...