US Patent Issued to Tokyo Metropolitan Institute of Medical Science on Nov. 4 for "Composition for inhibiting replication of hepatitis B virus" (Japanese Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,658, issued on Nov. 4, was assigned to Tokyo Metropolitan Institute of Medical Science.

"Composition for inhibiting replication of hepatitis B virus" was invented by Tsubasa Munakata (Tokyo), Michinori Kohara (Tokyo) and Takahiro Sanada (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a pharmaceutical composition for treating hepatitis B. The present invention provides a composition for inhibiting the replication of hepatitis B virus and a pharmaceutical composition for treating hepatitis B virus infection, each comprising an inhibitory substance against microRNA binding to the 5' epsilon signal sequence in the pre...