US Patent Issued to THERMO FINNIGAN on Sept. 23 for "Determination and correction of retention time and mass/charge shifts in LC-MS experiments" (California, Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,422,417, issued on Sept. 23, was assigned to THERMO FINNIGAN LLC (San Jose, Calif.).

"Determination and correction of retention time and mass/charge shifts in LC-MS experiments" was invented by Philip M. Remes (San Jose, Calif.) and Ping F. Yip (Salem, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods are described for the automatic determination and correction of retention time shift of a MS data set relative to a control data set, to correct for retention time drifts endemic to targeted LCMS analyses. In an embodiment, a 2D grid of periodic MS spectra versus time is collected for a control experiment, and RT windows are determined with an ...