US Patent Issued to The Wistar Institute on Feb. 10 for "Melanoma canine vaccine compositions and methods of use thereof" (Pennsylvania Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,433, issued on Feb. 10, was assigned to The Wistar Institute (Philadelphia).

"Melanoma canine vaccine compositions and methods of use thereof" was invented by Hildegund C. J. Ertl (Philadelphia) and Xiang Yang Zhou (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions and methods for generating a nucleic acid delivery system comprising a nucleic acid sequence encoding a heterologous protein comprising a canine tumor-specific antigen (canine melanoma polyepitope (K9Melapoly)) and an inhibitor of an immuno-inhibitory pathway (HSV-1 gD). Additionally, the current invention includes compositions and m...