US Patent Issued to The Wistar Institute of Anatomy and Biology on Nov. 18 for "DNA monoclonal antibodies targeting PD-1 for the treatment and prevention of cancer" (Pennsylvania Inventors)

ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,361, issued on Nov. 18, was assigned to The Wistar Institute of Anatomy and Biology (Philadelphia).

"DNA monoclonal antibodies targeting PD-1 for the treatment and prevention of cancer" was invented by David B. Weiner (Merion, Pa.) and Alfredo Perales Puchalt (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody or fragment thereof that targets programmed cell death protein 1 (PD-1). The disclosure also provides a method of preventing and/or treating disease, such as cancer, in a subject using the composition of the invention."

The patent...