ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,731, issued on June 10, was assigned to The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Md.).
"HLA-A24 agonist epitopes of MUC1-C oncoprotein and compositions and methods of use" was invented by Jeffrey Schlom (Potomac, Md.) and Kwong-Yok Tsang (Bethesda, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a human cytotoxic T lymphocyte (CTL) agonist epitope from the C-terminal subunit of mucin 1 (MUC1-C), which can be used as a peptide, polypeptide (protein), and/or in vaccine or other composition for the prevention or therapy of cancer. The invention further provides a nucleic acid enco...