ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,409,232, issued on Sept. 9, was assigned to The University of Tokyo (Tokyo).
"Temperature-responsive drug/polymer compound and application of compound to drug delivery" was invented by Kanjiro Miyata (Tokyo), Beob Soo Kim (Tokyo), Shigehito Osawa (Tokyo), Mitsuru Naito (Tokyo) and Hiroyuki Chaya (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "A drug-polymer conjugate having thermoresponsiveness includes at least one drug conjugated to at least one end portion of at least one thermoresponsive polymer segment having a lower critical solution temperature. The drug-polymer conjugate is capable of forming a micellular aggregate in an aqueous medium at...