US Patent Issued to The University of North Carolina at Chapel Hill on Nov. 11 for "UBE3A genes and expression cassettes and their use" (North Carolina, Texas Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,655, issued on Nov. 11, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).

"UBE3A genes and expression cassettes and their use" was invented by Benjamin David Philpot (Durham, N.C.), Steven James Gray (Southlake, Texas), Charles Shyng (Apex, N.C.) and Matthew Judson (Chapel Hill, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to polynucleotides comprising UBE3A open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of a UBE3A gene or aberrant ac...