US Patent Issued to The University of North Carolina at Chapel Hill on Feb. 3 for "Short-acting heparin-based anticoagulant compounds and methods" (American, Chinese Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,539,311, issued on Feb. 3, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).

"Short-acting heparin-based anticoagulant compounds and methods" was invented by Jian Liu (Chapel Hill, N.C.), Zhangjie Wang (Changchun, China), Po-Hung Hsieh (Pasadena, Calif.) and Yongmei Xu (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity...