US Patent Issued to The University of North Carolina at Chapel Hill, The Trustees of the University of Pennsylvania on July 15 for "Optimized GALC genes and expression cassettes and their use" (Texas, Pennsylvania Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,181, issued on July 15, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.) and The Trustees of the University of Pennsylvania (Philadelphia).

"Optimized GALC genes and expression cassettes and their use" was invented by Steven James Gray (Southlake, Texas), Erik Lykken (Dallas), Charles H. Vite (Philadelphia) and Allison Bradbury (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to polynucleotides comprising optimized GALC open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorder...