US Patent Issued to The University of North Carolina at Chapel Hill, Lincoln University on April 15 for "Optimized CLN5 genes and expression cassettes and their use" (New Zealander, American Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,948, issued on April 15, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.) and Lincoln University (Lincoln, New Zealand).

"Optimized CLN5 genes and expression cassettes and their use" was invented by Steven James Gray (Southlake, Texas), David Palmer (Christchurch, New Zealand) and Nadia Mitchell (Christchurch, New Zealand).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to polynucleotides comprising optimized CLN5 open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with abe...