ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,321, issued on March 25, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.) and Bamboo Therapeutics Inc. (Chapel Hill, N.C.).

"Optimized mini-dystrophin genes and expression cassettes and their use" was invented by Xiao Xiao (Chapel Hill, N.C.), Juan Li (Chapel Hill, N.C.), Chunping Qiao (Chapel Hill, N.C.), Scott W. J. McPhee (Chapel Hill, N.C.), Richard J. Samulski (Hillsborough, N.C.) and Maritza McIntyre (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to polynucleotides encoding mini-dystrophin proteins, viral vectors comprising the same, and methods of using the same for de...