US Patent Issued to The University of Chicago, Rush University Medical Center on Aug. 12 for "Materials and methods of using an inhibitor of plasminogen activation to treat anastomotic leak" (Illinois Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,579, issued on Aug. 12, was assigned to The University of Chicago (Chicago) and Rush University Medical Center (Chicago).

"Materials and methods of using an inhibitor of plasminogen activation to treat anastomotic leak" was invented by John C. Alverdy (Glenview, Ill.), Olga Y. Zaborina (Brookfield, Ill.) and Richard A. Jacobson (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is the de novo synthesis of phosphorylated polyethylene glycol compounds with three defined ABA (hy-drophilic/-phobic/-philic) structures: ABA-PEG10k-Pi10, ABA-PEG16k-Pi14, and ABA-PEG20k-Pi20 and linear polymer PEG20k-Pi20 absent of hydrophobic block. T...