US Patent Issued to The University of Chicago, IIT Research Institute on April 22 for "L-pag derivatives for treatment of sleep disordered breathing (SDB)" (Pennsylvania, Illinois Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,038, issued on April 22, was assigned to The University of Chicago (Chicago) and IIT Research Institute (Chicago).

"L-pag derivatives for treatment of sleep disordered breathing (SDB)" was invented by Michael J. Kates (Philadelphia), Nanduri R. Prabhakar (Chicago), David L. McCormick (Chicago) and Miguel Muzzio (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are novel Gamma- and Delta-propargyl carboxylic acids and esters. The novel compositions are antagonists of CSE and may be used to modulate of the activity of the carotid body, therefore providing therapeutic benefits for sleep-related breathing disorders and related cond...