US Patent Issued to THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES on Aug. 12 for "Compositions and methods to protect mammalian tissue against cold and other metabolic stresses" (Maryland Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,554, issued on Aug. 12, was assigned to THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES (Bethesda, Md.).

"Compositions and methods to protect mammalian tissue against cold and other metabolic stresses" was invented by Jingxing Ou (Bethesda, Md.), Wei Li (Potomac, Md.) and Kiyoharu Joshua Miyagishima (Laurel, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A composition for preserving viability of cells, tissues, or organs at a low temperature is provided. The composition includes a mitochondrial uncoupling agent, at least one protease inhibitor, and a reducing agent. Methods to protect cells, tis...