US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on Sept. 2 for "T cell receptors recognizing MHC class II-restricted MAGE-A3" (Maryland Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,317, issued on Sept. 2, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"T cell receptors recognizing MHC class II-restricted MAGE-A3" was invented by Paul F. Robbins (Chevy Chase, Md.), Steven A. Rosenberg (Bethesda, Md.) and Xin Yao (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides an isolated or purified T-cell receptor (TCR) having antigenic specificity for MHC Class II-restricted MAGE-A3. The invention further provides related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host...