ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,845, issued on Sept. 16, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).
"Methods of producing T cell populations using hydroxycitric acid and/or a salt thereof" was invented by Suman Kumar Vodnala (Bethesda, Md.), Nicholas P. Restifo (Chevy Chase, Md.), Rigel J. Kishton (Columbia, Md.) and Robert L. Eil (Chapel Hill, N.C.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods of producing an isolated population of T cells, the method comprising culturing isolated T cells in vitro in the presence of hydroxycitric acid, and/or a salt thereof, wherein...