US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on Oct. 14 for "T cell receptors recognizing HLA-A1-restricted MAGE-A3" (Maryland, California, New Hampshire Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,778, issued on Oct. 14, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"T cell receptors recognizing HLA-A1-restricted MAGE-A3" was invented by Paul F. Robbins (Chevy Chase, Md.), Steven A. Rosenberg (Potomac, Md.), Shiqui Zhu (Potomac, Md.), Steven A. Feldman (Redwood City, Calif.) and Richard A. Morgan (Center Harbor, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for a) melanoma antigen family A (MAGE A)-3 in the context of HLA-A1 or b) MAGE-A12 in the conte...