US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on Jan. 27 for "Anti-human papillomavirus 16 E7 T cell receptors" (Maryland Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,508, issued on Jan. 27, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"Anti-human papillomavirus 16 E7 T cell receptors" was invented by Christian S. Hinrichs (Bethesda, Md.) and Steven A. Rosenberg (Potomac, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a synthetic T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of human papillomavirus (HPV) 16 E7, E711-19. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provi...