US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on Dec. 9 for "High affinity monoclonal antibodies targeting glypican-2 and uses thereof" (Maryland Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,262, issued on Dec. 9, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"High affinity monoclonal antibodies targeting glypican-2 and uses thereof" was invented by Mitchell Ho (Urbana, Md.), Nan Li (Laurel, Md.) and Bryan D. Fleming (Bethesda, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Monoclonal antibodies that bind glypican-2 (GPC2) with high affinity are described. Immunotoxins and chimeric antigen receptors (CARs) that include the disclosed antibodies or antigen-binding fragments thereof are further described. In some instances, the antibody or antigen-...