US Patent Issued to The United States of America, as represented by the Secretary, Department of Health and Human Services on Aug. 19 for "Anti-KRAS-G12D T cell receptors" (American, Norwegian Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,742, issued on Aug. 19, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"Anti-KRAS-G12D T cell receptors" was invented by Eric Tran (Portland, Ore.), Yong-Chen Lu (Little Rock, Ark.), Anna Pasetto (Asker, Norway), Paul F. Robbins (Chevy Chase, Md.), Steven A. Rosenberg (Potomac, Md.) and Zhili Zheng (Gaithersburg, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule....