US Patent Issued to THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, UCL BUSINESS on Jan. 13 for "Therapeutics for the treatment of neurodegenerative disorders" (British, American Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,826, issued on Jan. 13, was assigned to THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Md.) and UCL BUSINESS LTD (London).

"Therapeutics for the treatment of neurodegenerative disorders" was invented by Pietro Fratta (London), Anna Leigh Brown (London), Oscar Wilkins (London), Matthew Keuss (London), Michael Ward (Bethesda, Md.) and Sarah Hill (Bethesda, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Antisense oligonucleotides (ASOs) are provided which are capable of modulating splicing by preventing inclusion of an UNC13A cryptic exon into an UNC13A mature mRNA. Such ASOs may be...