ALEXANDRIA, Va., April 9 -- United States Patent no. 12,270,881, issued on April 8, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human (Services Bethesda, Moldova).

"Denoising of dynamic resonance spectroscopic imaging using low rank approximations in the kinetic domain" was invented by Jeffrey R. Brender (Washington), James B. Mitchell (Damascus, Md.), Kazutoshi Yamamoto (North Bethesda, Md.), Shun Kishimoto (Rockville, Md.), Jeeva P. Munasinghe (Rockville, Md.), Hellmut Merkle (Bethesda, Md.) and Murali K. Cherukuri (Potomac, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Kinetic monitoring of in vivo metabolism of labelled tracers is based on ...