US Patent Issued to THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS on Nov. 25 for "Targeting intracellular target-binding determinants with intracellular antibodies" (California Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,925, issued on Nov. 25, was assigned to THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington).

"Targeting intracellular target-binding determinants with intracellular antibodies" was invented by Richard H. Weisbart (Sepulveda, Calif.) and Robert N. Nishimura (Sepulveda, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a method for inhibiting an intracellular target in a cell with a bispecific antibody comprising contacting the cell with a bispecific antibody having a first Fv fragment with a cell-penetrating determinant and a second Fv fragment with an intracellular target-binding ...