ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,453,760, issued on Oct. 28, was assigned to The UAB Research Foundation (Birmingham, Ala.) and Southern Research Institute (Birmingham, Ala.).
"Enhanced therapeutic usage of a purine nucleoside phosphorylase or nuceloside hydrolase prodrug" was invented by William B. Parker (Birmingham, Ala.) and Eric J. Sorscher (Birmingham, Ala.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The use of a purine nucleoside phosphorylase or nucleoside hydrolase or a vector encoding expression of one of these enzymes is detailed along with the use of a prodrug cleaved by the purine nucleoside phosphorylase or nucleoside hydrolase for the preparation of a direct injection...