US Patent Issued to The Trustees of the University of Pennsylvania on Sept. 30 for "Gene therapy for ceroid lipofuscinoses" (Pennsylvania, Connecticut, Maryland Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,653, issued on Sept. 30, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Gene therapy for ceroid lipofuscinoses" was invented by James M. Wilson (Philadelphia), Nathan Katz (Stamford, Conn.), Christian Hinderer (Baltimore) and Juliette Hordeaux (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods and compositions for treatment of Batten disease. Such compositions include a recombinant adeno-associated virus (rAAV), said rAAV comprising an AAV capsid, and a vector genome packaged therein, said vector genome comprising (a) an AAV inverted terminal repeat (ITR) sequence; (b) a promote...