ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,973, issued on Sept. 23, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).
"Methods and compositions for treatment of disorders and diseases involving RDH12" was invented by Jean Bennett (Bryn Mawr, Pa.), Junwei Sun (Philadelphia) and Vidyullatha Vasireddy (Wayne, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Codon optimized nucleic acid sequences for RDH12 are provided, as well as recombinant viral vectors, such as AAV, expression cassettes, proviral plasmids or other plasmids containing the codon optimized sequence for functional RDH12. Recombinant vectors are provided that express the codon optimized, functional...