ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,342, issued on Nov. 18, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Chimeric antigen receptor T regulatory cells for the treatment of atherosclerosis" was invented by Avery D. Posey (Philadelphia), Carl H. June (Merion Station, Pa.) and Robert D. Schwab (Bryn Mawr, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes compositions and methods for treating atherosclerosis. In certain embodiments, atherosclerosis is treated using a chimeric antigen receptor (CAR) T cell specific for modified low-density lipoprotein."

The patent was filed on April 26, 2019, under Application No. 17/050,52...