ALEXANDRIA, Va., June 10 -- United States Patent no. 12,291,699, issued on May 6, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Lung disease models on a chip" was invented by Dongeun Huh (Villanova, Pa.), Mark Mondrinos (Philadelphia) and Woo Yul Byun (Richland, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The presently disclosed subject matter provides a biomimetic lung disease model, and methods of its production and use. In one exemplary embodiment, the biomimetic lung disease model can include a first and second microchannel with a membrane coated with airway epithelial cells disposed between the microchannels and at least one device coupled to the biomimetic mod...