US Patent Issued to The Trustees of the University of Pennsylvania on May 20 for "Fully humanized anti-platelet factor 4 antibodies that treat heparin-induced thrombocytopenia" (Pennsylvania Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,304,948, issued on May 20, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Fully humanized anti-platelet factor 4 antibodies that treat heparin-induced thrombocytopenia" was invented by Mark I. Greene (Penn Valley, Pa.), Zheng Cai (Wynnewood, Pa.), Zhiqiang Zhu (Philadelphia) and Douglas B. Cines (Wynnewood, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are isolated antibodies or antibody fragments thereof that immunospecifically bind to platelet factor 4 (PF4). In some embodiments the isolated antibodies or antigen-binding fragments thereof comprise a light chain CDR and framework region comprising S...