US Patent Issued to The Trustees of the University of Pennsylvania on June 17 for "Methods and compositions for targeting retinoic acid for solid tumor immunotherapy" (Pennsylvania, Massachusetts Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,760, issued on June 17, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).

"Methods and compositions for targeting retinoic acid for solid tumor immunotherapy" was invented by Malay Haldar (Wynnewood, Pa.) and Samirkumar Devalaraja (Acton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions and methods comprising a retinoic acid receptor inhibitor, a retinoic X receptor inhibitor or an inhibitor of an enzyme in the retinoic acid biosynthesis pathway for treatment of a patient having a solid tumor. In some embodiments, the solid tumor is a sarcoma."

The patent was filed on Ma...